Whether you're looking for a romantic getaway or just need a place to stay while you're in town, there are many unique hotels in Chicago. We've got your guide to the best of the best. From upscale interiors to one-of-a-kind settings, you'll be blown away by these places to stay in the city. Keep scrolling to learn more.

1. 21 C Museum Hotel (formerly The James Hotel)

This boutique hotel has been recognized by leading travel magazines. Amenities include a spa, an award-winning steakhouse, and intriguing decor that is fresh and modern. the James Hotel is located near the shopping district and many attractions.

2. Hotel Lincoln

This Lincoln Park Hotel is situated near Wrigley Field, Lake Michigan, and one of the only free zoos in America. Guests enjoy a contemporary yet vintage vibe that carries from the lobby to the bar to your room. Most unique are the grand views of the city and green space below.

3. ACME Hotel

The Acme Hotel features a hip design that's perfect for millennials and the young at heart. Free coffee is delivered to guests each morning, and when not in their rooms, patrons enjoy spending time in the cocktail lounge, the hot tub, or out traversing the neighborhood.

4. The Blackstone Hotel

Famous for hosting presidents, notorious gangsters, and celebrities, the Blackstone Hotel is a getaway for those looking for true luxury. You'll find yourself near all the main attractions like Grant Park and the Chicago Art Institute, but you may never want to leave your room.

5. Industrial Loft

Live the way you wish you could at this Chicago Airbnb. Located near many diverse restaurants and bars in Irving Park, this loft is like a home away from home.

6. Longman & Eagle

Both a hotel and a restaurant, this wonderful Chicago attraction is the perfect place to stay. In addition to upscale drinks and dishes in the eatery, guests will also enjoy one of only six vibrant and urban rooms. Modern art and rustic decor make Longman & Eagle unique.

7. Villa D'Citta

One of the best bed & breakfasts in the country is Villa D'Citta, a Tuscan-style hotel situated in an old mansion from 1887. It offers luxurious rooms with royal amenities like whirlpool tubs and fireplaces. Breakfast includes European pastries, and there is always fresh fruit and cookies around.

8. The Langham

Featuring many luxurious suites, this downtown oasis is a must-stay at least once before you die. The Langham is sure to make your heart skip a beat with its lovely views and amenities.

Have you ever been to one of these unique hotels in Chicago? And if not, which one are you most excited to spend the night (or a few) at? Share your experiences with us! And while you're in the city, be sure to experience some of our iconic eats! If you've got a hankering for meat, check out our list of the best places to order Italian beef sandwiches in Chicago. Or perhaps you have more of a sweet tooth. Then, you'll want to take a look at our list of the best bakeries in Chicago where there are so many amazing options! So, many in fact that for Chicago cupcakes alone we had to make a separate list!