As local travel experts, we know what travelers are looking for when it comes to finding the perfect accommodations for their next trip. To compile our lists, we scour the internet to find properties with excellent ratings and reviews, desirable amenities, nearby attractions, and that something special that makes a destination worthy of traveling for.

Choosing the right place to stay can make or break your vacation. This is why we’ve come up with some of the best places to stay in South Carolina the next time you want to get away to The Palmetto State. Whether you’re on the hunt for the most affordable accommodation in South Carolina or want to find the most family-friendly vacation rentals in South Carolina, you’ve come to the right place. While you might be more prone to stick to Hilton Head Island and Myrtle Beach, we have a few other overnight suggestions to have you stepping outside the box. From Columbia to Charleston and beyond, ditch the Marriott beach resort and enjoy these Vrbo getaways.

Best Places to Stay in South Carolina for Families

Oftentimes the best places to stay in South Carolina are perfect for families. Whether the rental includes a pool, some family-friendly attraction, or otherwise, South Carolina has some pretty incredible places to stay with the whole brood.

Best Affordable Places to Stay in South Carolina

If you’re the type of traveler who would prefer to prioritize activities over accommodations, like taking to the golf course over posh linens, you don’t need to settle. Some of the most affordable vacation rentals in South Carolina also offer character and fun, too. Sometimes the best hotels can be a bit costly. Like that boutique hotel, you’ve been eyeing in historic Charleston. But just because you find a rental within a budget doesn’t mean it’s boring! Don’t sacrifice comfort or excitement when choosing where to stay in South Carolina because these rentals are low cost but big fun.

Best Romantic Places to Stay in South Carolina for Couples

Ahh, a romantic southern getaway. What better place to create the ultimate anniversary weekend than a state bursting with charm, culture, and history? Finding the right romantic accommodation in South Carolina doesn’t need to be difficult. All you need is a little privacy and a weekend open for possibility. But what could be more romantic than some oceanfront accommodations with views of the Atlantic and a Lowcountry hideaway on Lake Murray?

Best Places to Stay in Charleston

If you’re a vacationer who prefers history and character over a cabin in the woods, head on to the quaint city of Charleston. Situated right on the coast, Charleston is a gem worth spending a weekend exploring. Families can enjoy the walkable streets and proximity to the beach. Meanwhile, couples can enjoy romantic dinners and waterfront accommodations.

Best Places to Stay in Columbia

There’s no better way to see the beauty of South Carolina than with a visit to the capital city itself. Columbia offers so much in the way of beauty – whether it’s the historic district brick buildings or the quaint mom-and-pop shops. Some of the best places to stay in South Carolina can be found in this charming city, and they don’t include luxury hotels.

Have you already visited or stayed at any of these vacation rentals in South Carolina? Share with us your favorites in the comments section! Or, if you already know the best places to stay in South Carolina according to your travels, make sure to shout those out, too!

OnlyInYourState may earn compensation through affiliate links in this article.

More to Explore

Best Places to Stay in South Carolina

What are the best unique hotels in South Carolina?

The best unique hotels in South Carolina have one thing in common - they are each eccentric in their very own way. Some of the most unique South Carolina hotels include:

  • The Wilcox in Aiken
  • Cuthbert House Inn in Beaufort 
  • King Charles Inn in Charleston
  • The Grand Bohemian Lodge in Greenville
  • Red Horse Inn in Landrum
  • Battery Carriage House in Charleston 
  • Three Pines View in Salem

A few of these South Carolina hotels are incredibly historic, and many are located in small towns. Take The Wilcox as the perfect example. Award-winning, The Wilcox dates back to the late 19th century and offers the most in terms of southern hospitality.

Where are the most unique getaways in South Carolina? 

We’ve compiled the ultimate list of the most unique getaways in South Carolina in one list. These incredible day-trip adventures include:

  • Hunting Island State Park
  • Ripley's Aquarium
  • The Summit At Table Rock
  • Cape Romain Lighthouse Tour
  • Campbell's Covered Bridge
  • Pretty Place Chapel
  • Botany Bay
  • Lake Jocassee
  • Charleston Harbor
  • Glendale Shoals Heritage Preserve
  • Falls Park On The Reedy

With so many options for fun and unique getaways across South Carolina, there is a little bit of something for everyone on this list. Hunting Island State Park offers miles of beaches, creating an endless summer atmosphere. Meanwhile, Botany Bay has one of the most beautiful tree tunnels in the entire state!

Explore South Carolina