As local travel experts, we know what travelers are looking for when it comes to finding the perfect accommodations for their next trip. To compile our lists, we scour the internet to find properties with excellent ratings and reviews, desirable amenities, nearby attractions, and that something special that makes a destination worthy of traveling for.

Move over Charleston and Greenville, there’s a rising star now competing in the best South Carolina cities game! While Charleston has stolen the hearts of Travel + Leisure readers for over 10 years consecutively and Greenville was named a best main street in America for 2003, the city of Florence has broken the 20-year silent streak as one of only three 2023 Great American Main Street Award (GAMSA) winner. Let’s take a virtual trip to this Pee Dee region of South Carolina with a stop at a great restaurant, a fun attraction, and a cozy vacation home rental in Florence where you can stay when you take your own trip in real life to explore this top American city!

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Start planning your trip to this Great American city for a fun family getaway. You’ll find all the details on the vacation home rental in Florence we’ve highlighted on its Vrbo listing page.

Have you ever been to or through Florence before, perhaps while traveling I-95?

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