U.S. Route 50 is a 3,200-mile road that spans 11 states and showcases some of America’s most beautiful scenery — especially in Ohio. This route winds its way through the entire southern portion of Ohio, showing off some of the Buckeye State’s best rural scenery and most charming small towns. The roughly 200-mile stretch of Route 50 through Ohio is a beautiful drive everyone ought to experience.

Related Stories

Ohio's Longest State Highway, Route 7 Is A Scenic Drive Worth Taking

Ohio's Longest State Highway, Route 7 Is A Scenic Drive Worth Taking

Take A Scenic Drive Of Ohio Amish Country In One Day On This Road Trip

Take A Scenic Drive Of Ohio Amish Country In One Day On This Road Trip

The Stunning Ohio Drive That Is One Of The Best Road Trips You Can Take In America

The Stunning Ohio Drive That Is One Of The Best Road Trips You Can Take In America

Have you driven Route 50 through Ohio before? From Cincinnati to Athens, this is one glorious Ohio road trip you won’t soon forget!

Looking for more scenic drives in Ohio? How about a drive along the Amish Country Byway?

OnlyInYourState may earn compensation through affiliate links in this article. As an Amazon Associate, we earn from qualifying purchases.