Explore Missouri’s Best Waterfalls And Wineries On This Multi-Day Road Trip

While there are many things to love about the Show Me State, it doesn’t get any better than waterfalls, local wineries, and road trips. So, we sat down and combined all three! For an adventure that you are going to remember for years to come, embark on this multi-day road trip to some of the best waterfalls and local wineries in Missouri. We will take you from one end of the state to the other and to several Missouri destinations that you can cross right off of your bucket list.

This road trip in Missouri takes you approximately 870 miles and requires nearly 16 hours of drive time. You will want to plan for multiple days to complete this trip in its entirety, but we’ve got you covered. We’ve listed several conveniently located Best Western Hotels in Missouri along the way. Gas up the car, grab some snacks, and make sure your camera is ready to go — we are going on an adventure!

What do you think of our wineries and waterfalls road trip in Missouri? Are there any stops you would add to this itinerary? If so, let us and your fellow travelers know in the comments! And, during any of your travels or additional road trip adventures, make sure to book a stay at the closest Best Western property to you!

Address: 2038 State Hwy 86, Lampe, MO 65681, USA
Address: Grand Falls Road, Grand Falls Rd, Joplin, MO 64804, USA
Address: 148 Taum Sauk Trail, Middle Brook, MO 63656, USA
Address: 6470 Hwy F, Farmington, MO 63640, USA
Address: Hodgson Water Mill, Dora, MO 65637, USA
Address: 5870 Historic Rte 66, Leasburg, MO 65535, USA
Address: 846 Winery Hills Estate, Linn Creek, MO 65052, USA
Address: 13986 Hwy C, Rayville, MO 64084, USA